SANTA CLARA — The 49ers added depth at defensive end and safety Monday with two call-ups from the practice squad.

Defensive end Sam Okuayinonu and safety Tracy Walker III were pulled from the practice squad to be available for Monday night’s Week 1 game against the New York Jets. They will serve as reserve roles with defensive end Yetur Gross-Matos and safety Talanoa Hufanga out.

The 49ers also signed All-Pro left tackle Trent Williams off the reserve/non-reporting list, allowing him to return to his starting position for the 2024 season opener at Levi’s Stadium.

The 49ers released veteran offensive tackle Brandon Parker from the 53-man roster to make room for Williams. Parker re-signed with the team last week, while Williams stayed away from the team as a holdout during contract negotiations.

Williams eventually agreed to a new three-year deal worth $82.66 million, with $48 million fully guaranteed. After he reported to the team, the 49ers were cleared for waivers and didn’t have to make a move right away.

Hufanga is set to return to action after suffering a season-ending torn ACL last November. He practiced limited last week and the 49ers listed him as questionable for the season opener.

Ji’Ayir Brown and George Odum are expected to be the 49ers’ starting safeties.

Walker could be the 49ers’ No. 3 safety ahead of rookie Malik Mustapha. Walker has plenty of experience going up against quarterback Aaron Rodgers, having played six seasons with the Detroit Lions, making 43 starts in 79 games.

Rodgers played his first 18 NFL seasons in the NFC North with the Green Bay Packers before being traded to the Jets last year.

The 49ers added some depth on the perimeter with Gross-Matos out after suffering a right knee injury in San Francisco’s final preseason game.

Nick Bosa and Leonard Floyd are the 49ers’ starting defensive ends, while Robert Beal Jr. and Okuayinonu are expected to see action as part of the team’s defensive line rotation.

Running back Christian McCaffrey and left guard Aaron Banks are questionable and the 49ers must turn over their list of 48 active players for the game 90 minutes before the 5:15 p.m. kickoff.

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