Rams: WR Cooper Kupp (ankle, out); TE Davis Allen (back, out); K Joshua Karty (groin, possible last-minute decision); CB Cobie Durant (toe, expected to play); DL Bobby Brown III (ankle, expected to play).

49ers: RB Christian McCaffrey (Achilles, on the injured list); WR Deebo Samuel (calf, out), TE George Kittle (hamstring, questionable), DE Nick Bosa (rib, questionable); CB Charvarius Ward (hamstring/knee, questionable).