Two weeks ago, this game looked like an opportunity for the Chargers to make a major division statement. Now it’s just about survival.

With injuries to four key starters and a one-game suspension for star safety Derwin James Jr. the Chargers (2-1) are hoping to at least enter the off week without adding anyone else to the injury report.

Quarterback Justin Herbert will try to resolve a high ankle sprain behind an offensive line that may be without starting tackles Rashawn Slater (chest) and Joe Alt (knee). Outside linebacker Joey Bosa is dealing with a hip injury that limited him to just two appearances against the Pittsburgh Steelers.

Chiefs tight end Travis Kelce has had a quiet start to the season with eight catches for 69 yards and no touchdowns as the Chiefs (3-0) struggled to convert in the red zone, but the All-Pro has a history of terrorizing the Chargers. He averaged 105.8 yards in the last eight games against the Chargers, with eight touchdowns. The Chiefs have won five in a row against their AFC West rivals, four of which came on one possession.