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    • Arizona Cardinals vs Buffalo Bills Score Updates for NFL Week 1 Game
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    Arizona Cardinals vs Buffalo Bills Score Updates for NFL Week 1 Game

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    The Arizona Cardinals open their 2024 NFL regular season with a Week 1 NFL game against the Buffalo Bills on Sunday, September 8.

    The Cardinals were 4-13 last season. The Bills went 11-6.

    Follow our live updates from the game, which will be played at Highmark Stadium in Orchard Park, New York, for the latest scores, news, notes and analysis from NFL Week 1 contest.

    Kyler Murray completed 16 of 19 passes for 131 yards and a touchdown as the Arizona Cardinals led the Bills 20-17 at halftime.

    Bills QB Josh Allen scrambled for a touchdown in the final seconds of the first half to pull the Bills within a score. Buffalo will get the running back to start the second half.

    Allen is 5-for-5 passing for 76 yards. He has three carries for 20 yards. He has two sacks and a fumble.

    Murray leads the Cardinals with 29 rushing yards on three carries. James Cook leads Buffalo with 49 yards on eight carries.

    Score: Cardinals 17, Bills 10 (halftime)

    Cardinals running back James Conner was the workhorse on the team’s first drive, but the ball went to Michael Wilson for the touchdown.

    By the end of the second quarter, the Cardinals were crumbling down the field with Trey Benson at running back. The rookie had three carries for 19 yards. But when it came time to put the ball in the end zone, it was Conner time.

    Conner came in to carry the ball 3 yards for a touchdown. Matt Prater added the run after for a 17-3 lead.

    Score: Cardinals 17, Bills 3 (2:40 Q2)

    The first pass thrown to Cardinals rookie WR Marvin Harrison Jr. bounced off the receiver’s hands.

    The Cardinals went straight back to Harrison on the next play for a gain of 4 yards.

    A touchdown by Bills QB Josh Allen was negated by an offensive face mask penalty. The Bills had to settle for a 37-yard field goal.

    It was the second disappointing drive for the home team, who lost the first possession of the ball.

    The Cardinals outscored the Bills 120-76 and dominated time of possession.

    Allen is 2-for-2 passing for 37 yards. James Cook has 49 yards on eight carries.

    Cardinals QB Kyler Murray is 10-for-11 with 87 yards and a touchdown. He leads the team in rushing with two carries for 17 yards.

    Score: Cardinals 10, Bills 3 (9:47 Q2)

    Bills quarterback Josh Allen fumbled on a sack. The ball was recovered by Justin Jones for the Cardinals.

    The Cardinals worked their way to Buffalo’s 12-yard line before the drive stalled.

    Arizona used that bonus possession to convert a 29-yard field goal via Matt Prater.

    Score: Cardinals 10, Bills 0 (14:57 Q2)

    Matt Prater bounced a kickoff to the Buffalo 2-yard line where Bills Brandon Codrington picked it up. He returned the ball 53 yards.

    The Bills began their first offensive series at the Arizona 45-yard line.

    Kyler Murray completed a 5-yard pass to Michael Wilson for the Cardinals’ first TD of the young season. Matt Prater’s punt afterward made it 7-0.

    The drive covered 70 yards and consisted of 13 plays.

    Murray was 4-for-5 for 44 yards on the drive. Marvin Harrison Jr. was targeted once along the sideline but did not catch the ball.

    The drive extended on a third down play where Murray had to run 6 yards before sliding. The Bills were penalized for unnecessary roughness, giving the Cardinals 10 yards and a first down.

    Score: Cardinals 7, Bills 0 (7:47 Q1)

    Running back James Conner had the first five touches for the Arizona Cardinals with three carries and two catches. After Kyler Murray completed an 8-yard pass to Greg Dortch, the ball went to Conner again.

    In the first 4 minutes of the game, Conner had 40 yards.

    Score: Cardinals 0, Bills 0 (10:37 Q1)

    Cardinals vs Bills Schedule: What Time is the NFL Week 1 Game?

    The contest is on Sunday, September 8 at 10am MST, 1pm ET.

    Who will win the NFL Week 1 game? Arizona Cardinals vs Buffalo Bills Predictions, Odds & Chances

    Cardinals vs Bills Location: Where is the NFL Week 1 Game?

    The match will be played at Highmark Stadium in Orchard Park, New York.

    Cardinals vs Bills TV: What Channel Will the NFL Week 1 Game Be Aired On?

    The match will be broadcast on CBS.

    NFL Week 1 Schedule: TV Channels, How to Watch, Streaming Games

    Cardinals vs Bills streaming: How can I live stream the NFL Week 1 game?

    Streaming options for the game include Paramount+, CBS’s streaming service, and FUBO, which offers a free trial.

    Cardinals vs. Bills Announcers: Who’s Covering Week 1 NFL Game?

    Tom McCarthy (play-by-play), Ross Tucker (analyst) and Jay Feely (analyst) are expected to serve as commentators for the Cardinals during the Bills’ Week 1 NFL game.

    NFL Week 1 Announcers: TV Networks Announce Teams for Week 1 NFL Schedule

    Cardinals vs Bills Game Odds: Who’s the Favorite in NFL Week 1?

    According to BetMGM Sportsbook’s NFL Week 1 odds, the Bills are a six-point favorite over the Cardinals in this game.

    Buffalo is -275 on the moneyline, while Arizona is +220.

    The over/under (point total) is set at 48 points.

    NFL Week 1 Odds: Point spreads, moneylines, over/unders for match betting

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    We occasionally recommend products and services of interest. If you make a purchase by clicking on one of the links, we may earn an affiliate fee. USA TODAY Network newsrooms operate independently and this does not influence our reporting.

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