The Raiders were winning midway through the fourth quarter when head coach Antonio Pierce was faced with a choice.

Trailing 16-10, Las Vegas had a fourth-and-1 attempt from the Chargers’ 43-yard line.

What would you do there?

Pierce decided to go for a punt, but the ball was caught at the Los Angeles 8-yard line.

But eight plays and 92 yards later, the Chargers scored a touchdown to make it 22-10 — the final score of the game.

The Raiders’ defense had played well up to that point, but Pierce’s decision to trust the unit didn’t pay off. Running back J.K. Dobbins gained 2 yards to move the chains on third-and-2 from the Chargers’ 16. A play later, Dobbins gained 61 yards on second-and-3 to put Los Angeles at the visitors’ 14.

On third-and-6 from the Las Vegas 10-yard line, Justin Herbert passed the rookie receiver’s first career touchdown to Ladd McConkey to put the Chargers ahead by a big margin.

Dobbins had just 8 yards in the first half, but was terrific in the second half, finishing with 135 yards on 10 carries. His 12-yard touchdown early in the fourth quarter gave Los Angeles a 16-7 lead.

Herbert was 17-of-26 passing for 144 yards with a touchdown. McConkey finished with five receptions for 39 yards.

Chargers edge rushers Joey Bosa and Khalil Mack also played well, as Bosa finished with seven tackles and a sack. Mack had 1.5 sacks on the day.

Las Vegas’ offense couldn’t really get going and was plagued by turnovers. Minshew wasn’t lined up with a receiver and had a backward pass to no one going for a fumble in the first half. Running back Zamir White had the ball knocked out while making a decent run for a fumble.

Minshew finished 25 of 33 for 257 yards with a touchdown and an interception. White had 44 yards on 13 carries. Davante Adams caught five passes for 59 yards. In his debut, first-round pick Brock Bowers had six catches for 58 yards.

The only time the Raiders reached the end zone was on a swing pass from Minshew to running back Alexander Mattison, which went 31 yards to the house.

Jim Harbaugh is now 1-0 as the Chargers’ head coach, making his debut in the role more than two decades after starting as the team’s quarterback.

Pierce is now 0-1 as the team’s permanent head coach after serving as interim coach last year.

Las Vegas hits the road again next week when the club travels to the East Coast to take on Baltimore.

The Chargers will also play on the East Coast, taking on the Panthers in Charlotte.